Alert on shift.
Real sleep after.

Cordyceps militaris

Cordyceps contains a compound called cordycepin that increases cellular energy production — particularly in the brain — by blocking the same chemical signal that makes us feel tired. Traditionally used in Tibet for endurance at altitude. Studied in athletes for exercise tolerance and in animal models for cognition under fatigue.

L-tyrosine

Tyrosine is an amino acid your brain converts directly into dopamine and norepinephrine — the chemicals that handle focus, motivation, and stress tolerance. Under cognitive load or sleep deprivation, your brain burns through these faster than it makes them. Supplemental tyrosine refills the supply.

Caffeine anhydrous (sustained-release microcapsule)

Caffeine blocks adenosine, the molecule that builds up over your waking hours and makes you sleepy. Standard caffeine spikes and falls off in 4 hours. The slow-release form keeps you alert across a full 8–12 hour shift without the second-hour jitter or the fifth-hour crash. Paired with L-theanine, the result is steady focus rather than wired-and-tired.

L-theanine (from green tea)

L-theanine is the amino acid in green tea that makes a green-tea caffeine boost feel calm rather than jittery. It produces alpha-wave brain activity (the same pattern as relaxed focus and meditation) and softens caffeine's edge without blunting its alertness benefit.

Cytidine 5'-diphosphocholine

Your brain uses a chemical called acetylcholine to form and recall memories. Citicoline is the raw material your brain needs to make it. As we age, supply drops; this delivers it directly.

6S-5-methyltetrahydrofolate glucosamine salt

Folate is the raw material your body uses to keep nerve cells healthy and to recycle a toxic byproduct (homocysteine) that accelerates brain shrinkage. The VITACOG trial showed the right form of folate plus B12 and B6 cut brain shrinkage by 30–50% in older adults.

Methylcobalamin

B12 maintains the protective insulation around nerve fibers and works with folate to keep brain-aging biomarkers in check. B12 deficiency is one of the most common — and most missed — causes of brain fog and fatigue in adults over 50.

Ganoderma lucidum

Reishi is the most-studied calming mushroom in traditional medicine. Long-chain sugars (beta-glucans) help with sleep onset; bitter compounds (triterpenes) quiet the stress-hormone response. You need both extractions to get both effects.

Magnesium L-threonate

Most magnesium supplements never make it past your stomach into your brain. Magtein® uses a special carrier that gets magnesium across the blood-brain barrier. Brain magnesium is required for the kind of deep, restorative sleep that gets thinner with age.

Glycine

Falling asleep depends on your body cooling down. Glycine triggers that cool-down by opening small blood vessels in your hands and feet, releasing heat. It also calms the brain's arousal signals. The result: shorter time to fall asleep, deeper sleep, less daytime fatigue.

N-acetyl-L-cysteine (reduced dose)

Your body makes its own primary antioxidant called glutathione. The rate-limiting ingredient is cysteine — NAC is the bioavailable form that gets it where it needs to go. Helps the body clear oxidative damage that accumulates faster under sleep deprivation.

Withania somnifera (root extract)

Ashwagandha is an adaptogen — a plant that helps the body return to baseline after stress. The most consistent finding across trials is that it lowers cortisol (the stress hormone) and improves sleep onset.

Magnolia officinalis bark extract

Honokiol and magnolol act on the same brain target as anti-anxiety medications (the GABA system) — but at a gentle modulating level, not a blunt switch. The result is faster sleep onset and quieter mental chatter at bedtime without the next-morning fog or the tolerance that builds up with pharmaceutical sedatives.

Melatonin (N-acetyl-5-methoxytryptamine)

Melatonin is the hormone your brain releases at night to tell your body it's time to sleep. Shift workers need to override that signal — sleeping during the day, when their natural production is suppressed. A microdose mimics the natural release pattern; a megadose blunts the body's own clock.

Gastrodia elata (tian ma)

Gastrodin acts on multiple brain systems at once — it gently engages the same calming receptor system as magnolia (GABA), supports the production of growth factors that protect brain cells, and reduces inflammation in the brain. Preclinical work in sleep-deprivation models shows it helps recover from circadian disruption.

Urolithin A

Inside every cell are tiny power plants called mitochondria. They wear out with age. Urolithin A is a compound your body makes from pomegranate and berries — but only if you have the right gut bacteria, which most people don't. It triggers your cells to recycle their worn-out power plants.

L-ergothioneine

Ergothioneine is an antioxidant your body can't make (so you have to eat it) but specifically goes out of its way to absorb. It accumulates in mitochondria — the cell's power plants — and especially in the brain. Falling blood levels are an early warning sign of cognitive decline.