Sceletium tortuosum (Zembrin®)

Mechanism

Zembrin® is a standardized extract of the South African plant kanna. It takes the edge off acute stress quickly — brain-imaging studies show it quiets the threat-detection circuitry — but without sedating you. The point is calmer, not slower.

Why we use it

High-stakes focus often requires acute anxiety modulation. Zembrin is the only botanical with replicated fMRI amygdala-decoupling signal at supplement doses.

How we dose it

Hericea uses 25 mg per serving (per AM stick pack). The clinical trial range that anchors this dose is 25–50 mg/day.

At the Zembrin® clinical RCT dose. Mesembrine-alkaloid-standardized branded form.

Quality & sourcing

Zembrin® HG&H Pharmaceuticals branded; mesembrine-alkaloid standardized.

HG&H Pharmaceuticals-licensed.

Cautions

• consult physicianConsult physician if on SSRI/SNRI/MAOI antidepressants.